Diffrences Between Drug Addiction and Tolerance - OnePharmily OnePharmily: Diffrences Between Drug Addiction and Tolerance
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Monday, 12 November 2018

Diffrences Between Drug Addiction and Tolerance

The term 'addiction' refers to compulsive drug use- (the entire substance-dependence syndrome). It is a cluster of symptoms indicating that the individual continues use of the substance despite significant substance-related problems.

Medical addict is a term used to describe a patient in treatment for a medical disorder who has become "addicted" to the available prescribed drug; the patient begins taking them in excessive doses, out of control. Example of this is like someone having chronic pain who begins using the prescribed, medication more often than directed by the physician.

Tolerance is the most common response repetitive use of the same drug. It can be defined as the reduction in response to the drug after repeated administrations.

 For example a person taking a drug on a normal dose, as the dose of the drug increases, the observed effect of the drug wii also increase. But, with a repeated use of the drug, tolerance begins to develope. So, a higher dose of the drug is required to produce the same effect that was once obtained with a lower dose. 

Diazepam is known to cause sedation at a dose of 5-10 mg in a first-time user, but with repitative use, a higher dose of hundreds of milligrams is required to produce same effect; some abusers have had documented tolerance to more than 1000 mg/day

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