Rapid Revision: Glatiramer Acetate (Basic Facts) - OnePharmily OnePharmily: Rapid Revision: Glatiramer Acetate (Basic Facts)
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Thursday, 11 October 2018

Rapid Revision: Glatiramer Acetate (Basic Facts)

All facts about glatiramer acetate

Fact 1: Glatiramer acetate is a medicine used to treat multiple sclerosis. It is used to reduce the number of relapses though it does not reduce progression of
the disease. 

Fact 2: It is a mixture of the following four peptides glutamic acid, lysine, alanine and tyrosine. 

Fact 3: It is taken as a subcutaneous injection.

Fact 4: Mechanism of action - 

  • Glatiramer acetate is an immunomodulator that works by suppressing the immune response.
  • It achieves this, in part, by shifting T-cell population from proinflammatory Thl cells to regulatory Th2 cells. It may act as a decoy to divert the immune response away from myelin. 


Fact 5: Glatiramer acetate is classified as pregnancy category B - meaning "no risk in non-human studies".

Fact 6: An initial injection site reaction composed of anxiety, shortness of breath, flushing and rapid heartbeat may occur within the first 30 minutes of use

Fact 7: Side effects include - 
Injection site reactions
Lipatrophy at inj. site
Aches
Fever
Chills
Vasodilation / Chest pain
Lymphadenopathy
Nausea
Shortness of breath
Weight gain
Rash

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