Fast Revision - All facts you must know about Etarnercept - OnePharmily OnePharmily: Fast Revision - All facts you must know about Etarnercept
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Wednesday, 3 October 2018

Fast Revision - All facts you must know about Etarnercept

All facts about Etarnercept

Fact 1: Etanercept is a medicine used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis and ankylosing sponylitis. It is also
used to treat juvenile idiopathic arthritis in children.

Fact 2: Etanercept is a fusion protein produced by recombinant DNA. It is administered via the SC route.

Fact 3: Mechanism of action -

  • Etanercept is a TNF inhibitor tumor necrosis factor alpha being the "master regulator" of the inflammatory response.
  •  Etanercept acts as a "decoy receptor" that binds to TNF reducing the inflammatory response characteristic of autoimmune disease.

Fact 4: Reactivation of serious infections such as latent TB and hepatitis B have been reported.

Fact 5: It is classified as pregnancy category B meaning "no risk in non-human studies". It has a half-life of approximately 100 hours.

Side effects include:
Respiratory infections
Injection site reactions
GI effects
Skin rash

It will be helpful to read the super awesome Mnemonics for all antiinflammatory drugs

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